Detalhe da pesquisa
1.
Isavuconazole versus voriconazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE): a phase 3, randomised-controlled, non-inferiority trial.
Lancet
; 387(10020): 760-9, 2016 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26684607
2.
Safety and pharmacodynamic dose response of short-term prednisone in healthy adult subjects: a dose ranging, randomized, placebo-controlled, crossover study.
BMC Musculoskelet Disord
; 17: 293, 2016 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27424036
3.
Diarrhea-predominant irritable bowel syndrome: creation of an electronic version of a patient-reported outcome instrument by conversion from a pen-and-paper version and evaluation of their equivalence.
Patient Relat Outcome Meas
; 8: 83-95, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28790875
4.
Evaluation and performance of a newly developed patient-reported outcome instrument for diarrhea-predominant irritable bowel syndrome in a clinical study population.
Therap Adv Gastroenterol
; 10(9): 673-687, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28932269
5.
Cultural adaptation: translatability assessment and linguistic validation of the patient-reported outcome instrument for irritable bowel syndrome with diarrhea.
Patient Relat Outcome Meas
; 7: 81-92, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27382346
6.
A Phase 1 Dose-Escalation Study of ASP2409, a Selective T-Cell Costimulation Inhibitor, in Stable Rheumatoid Arthritis Patients on Methotrexate Therapy.
Clin Pharmacol Drug Dev
; 5(4): 259-68, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27310327
7.
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of ASP2408, a Potent Selective T-Cell Costimulation Modulator After Single and Multiple Ascending Doses in Healthy Volunteers and RA Patients.
Clin Pharmacol Drug Dev
; 5(5): 408-25, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27410490
8.
Isavuconazole treatment for mucormycosis: a single-arm open-label trial and case-control analysis.
Lancet Infect Dis
; 16(7): 828-837, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26969258
9.
Long-term maintenance of response across multiple fibromyalgia symptom domains in a randomized withdrawal study of pregabalin.
Clin J Pain
; 28(7): 609-14, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22688598
10.
Safety profile and tolerability of up to 1 year of pregabalin treatment in 3 open-label extension studies in patients with fibromyalgia.
Clin Ther
; 34(5): 1092-102, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22503162
11.
Maraviroc, a chemokine receptor-5 antagonist, fails to demonstrate efficacy in the treatment of patients with rheumatoid arthritis in a randomized, double-blind placebo-controlled trial.
Arthritis Res Ther
; 14(1): R11, 2012 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22251436
12.
An international, randomized, double-blind, placebo-controlled, phase III trial of pregabalin monotherapy in treatment of patients with fibromyalgia.
J Rheumatol
; 38(12): 2643-52, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21965636
13.
Exposure-response analyses of the effects of pregabalin in patients with fibromyalgia using daily pain scores and patient global impression of change.
J Clin Pharmacol
; 50(7): 803-15, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20357295
14.
Impact of a soluble phospholipase A2 inhibitor on inhaled allergen challenge in subjects with asthma.
J Asthma
; 42(1): 65-71, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15801331
15.
LY315920NA/S-5920, a selective inhibitor of group IIA secretory phospholipase A2, fails to improve clinical outcome for patients with severe sepsis.
Crit Care Med
; 33(8): 1741-8, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16096451
16.
Neutrophil elastase and acute lung injury: prospects for sivelestat and other neutrophil elastase inhibitors as therapeutics.
Crit Care Med
; 30(5 Suppl): S281-7, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12004249
17.
Neutrophil elastase inhibition in acute lung injury: results of the STRIVE study.
Crit Care Med
; 32(8): 1695-702, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15286546